1-Deoxymannojirimycin hydrochloride
CAS No. 73465-43-7
1-Deoxymannojirimycin hydrochloride ( —— )
Catalog No. M27591 CAS No. 73465-43-7
1-Deoxymannojirimycin hydrochloride is a selective α1,2-mannosidase inhibitor(IC50: 20 μM). 1-Deoxymannojirimycin hydrochloride also inhibits HIV‐1 strains and has poor antiviral activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product Name1-Deoxymannojirimycin hydrochloride
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NoteResearch use only, not for human use.
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Brief Description1-Deoxymannojirimycin hydrochloride is a selective α1,2-mannosidase inhibitor(IC50: 20 μM). 1-Deoxymannojirimycin hydrochloride also inhibits HIV‐1 strains and has poor antiviral activity.
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Description1-Deoxymannojirimycin hydrochloride is a selective α1,2-mannosidase inhibitor(IC50: 20 μM). 1-Deoxymannojirimycin hydrochloride also inhibits HIV‐1 strains and has poor antiviral activity.(In Vitro):Exposure of such mutant virus strains to 1-Deoxymannojirimycin results in an enhanced suppression of mutant virus-induced cytopathicity in CEM cell cultures.When combined with CBAs at concentrations that showed poor if any suppression of mutant virus replication as single drugs, a synergistic antiviral activity of 1-Deoxymannojirimycin was observed.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorPPARβ;PPARδ
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Research Area——
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Indication——
Chemical Information
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CAS Number73465-43-7
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Formula Weight199.6
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Molecular FormulaC6H14ClNO4
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Purity>98% (HPLC)
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Solubility——
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SMILESCl.OC[C@H]1NC[C@@H](O)[C@@H](O)[C@@H]1O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Kaupang ?, et al. Synthesis, biological evaluation and molecular modeling studies of the PPARβ/δ antagonist CC618. Eur J Med Chem. 2015 Apr 13;94:229-36.
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